High prevalence of human antibodies to recombinant Duffy binding-like alpha domains of the Plasmodium falciparum-infected erythrocyte membrane protein 1 in semi-immune adults compared to that in nonimmune children.

Title:

Dataset

identifier:	1337984
description:	epitope description:LARSFADIGDIVRGKDLY antigen name:Erythrocyte membrane protein 1, PfEMP1 (UniProt:O96296) host organism:Homo sapiens
aggregation:	instance of dataset
availability:	available
primaryPublications:	11705939

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1002624
landingPage:	http://www.iedb.org/assay/1337984

Publication

type:	Literature
publicationVenue:	Infect Immun
dates:	2001

Dimension

study type:	b cell assays
subject species:	Plasmodium falciparum

Person

fullName:	R M Oguariri S Borrmann M Q Klinkert P G Kremsner J F Kun

Data Type

method:	ELISA

Study

name:	High prevalence of human antibodies to recombinant Duffy binding-like alpha domains of the Plasmodium falciparum-infected erythrocyte membrane protein 1 in semi-immune adults compared to that in nonimmune children.
description:	Highly reactive sera from semi-immune individuals were tested by ELISA against the conserved peptide and nine GST fusion proteins containing the conserved epitope of Duffy binding-like alpha domains from different isolates. However, the peptide had no effect in competition ELISA against fusion proteins.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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