Immunological Data Discovery Index
Immunological Data Discovery Index
| authorizations: |
registration not required
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| accessURL: |
http://www.iedb.org/reference/1002948 |
| landingPage: |
http://www.iedb.org/assay/1342878 |
| type: |
Literature
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| publicationVenue: |
J Immunol
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| dates: |
1992
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| study type: | b cell assays |
| subject species: | Plasmodium falciparum K1 |
| fullName: |
A Kumar
R Arora
P Kaur
V S Chauhan
P Sharma
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| method: |
ELISA
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| name: |
""Universal"" T helper cell determinants enhance immunogenicity of a Plasmodium falciparum merozoite surface antigen peptide.
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| description: |
The authors identify this epitope as having been derived from the P. falciparum major merozoite surface antigen (PMMSA, gp195). The provided sequence does not match the current SP/Genbank database sequences. It is cited to be derived from the K1 strain sequence as published in J. Mol. Blol. 195:273. In that reference the sequence provided matches the current SP/Gb sources, with a D6, K19 and T20.
When 12 inbred mice strains were belonging to 7 different H-2 haplotypes were immunized with the epitope, only one (SJL, H-2:s) responded with a high anti-p8 titer as measured on day 70 p.i..
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| name: |
iedb
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| homePage: |
http://www.iedb.org |
