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identifier: 1343099
description:
epitope description:SKKHTARDGE
antigen name:Gametocyte surface protein P230
host organism:Mus musculus
aggregation:
instance of dataset
availability:
available
primaryPublications: 10583858
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1002794
landingPage: http://www.iedb.org/assay/1343099
type:
Literature
publicationVenue:
Parasite Immunol
dates:
1999
study type: b cell assays
subject species: Plasmodium falciparum
fullName:
A A Vincent
S Fanning
F C Caira
K C Williamson
method:
western blot
name:
Immunogenicity of malaria transmission-blocking vaccine candidate, y230.CA14 following crosslinking in the presence of tetanus toxoid.
description:
A cysteine was included at the carboxy-terminus of this peptide for conjugation to the commercial maleimide-activated SuperCarrier
Recognition of the upper band of the 310 kDa doublet of Pfs230 is seen in immunoblots of gamete extracts when developed with anti-peptide antibodies. It is mentioned that the unprocessed 363 kDa form is also detected from gametocyte extracts, but that since that form is scarce in gametes, it cannot be detected here. Immunoprecipitation experiments of radiolabeled extract yielded negative results.

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