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identifier: 1340202
description:
epitope description:WNDLSNRKLVGKINTNSKYVHRNKKNDKLYRDEWWKVIKK
antigen name:Erythrocyte binding antigen 175
host organism:Aotus nancymaae
aggregation:
instance of dataset
availability:
available
primaryPublications: 15890273
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1002766
landingPage: http://www.iedb.org/assay/1340202
type:
Literature
publicationVenue:
J Struct Biol
dates:
2005
study type: b cell assays
subject species: Plasmodium falciparum
fullName:
Fabiola Espejo
Adriana Bermú
dez
Magnolia Vanegas
Zuly Rivera
Elizabeth Torres
Luz Mary Salazar
Manuel Elkin Patarroyo
method:
ELISA
name:
Elongating modified conserved peptides eliminates their immunogenicity and protective efficacy against P. falciparum malaria.
description:
After immunization with a polymerized preparation of this peptide, there is significant reactivity towards the monomeric peptide and to the N terminal half but not towards the C-terminal end, which has the red blood cell binding activity. The response obtained failed to provide protection against experimental challenge with the parasite.

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