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Title: Synthesis of a diepitope multiple antigen peptide containing sequences from two malaria antigens using Fmoc chemistry.
identifier: 1340719
description:
epitope description:VTEEIVTEEIVTEEI
host organism:Mus musculus C57BL/10 X DBA/2
antibody name:B10.D2
aggregation:
instance of dataset
availability:
available
primaryPublications: 7533196
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1002798
landingPage: http://www.iedb.org/assay/1340719
type:
Literature
publicationVenue:
J Immunol Methods
dates:
1995
study type: b cell assays
subject species:
fullName:
N Ahlborg
method:
ELISA
name:
Synthesis of a diepitope multiple antigen peptide containing sequences from two malaria antigens using Fmoc chemistry.
description:
This artificial epitope is based upon the naturally occurring repeat sequence VTEEI from Plasmodium falciparun Pf332.
Sera from mice immunized with a MAP construct containing 8 copies of the epitope recognized the epitope as presented in two MAP constructs: one consisting of 4 copies of the epitope linked to a lysine core, the other consisting of 2 copies of the epitope and 2 copies of another P falciparum epitope, (DPNANPNV)2 linked to a lysine core. The epitope containing MAP constructs also inhibited the binding of the sera to the same MAPs.

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