Immunological Data Discovery Index
Immunological Data Discovery Index
| authorizations: |
registration not required
|
| accessURL: |
http://www.iedb.org/reference/1002859 |
| landingPage: |
http://www.iedb.org/assay/1341090 |
| type: |
Literature
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| publicationVenue: |
J Clin Invest
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| dates: |
1996
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| study type: | b cell assays |
| subject species: | Plasmodium yoelii yoelii |
| fullName: |
G Mor
G Yamshchikov
M Sedegah
M
R Wang
R A Houghten
S Hoffman
D M Klinman
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| method: |
ELISA
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| name: |
Induction of neonatal tolerance by plasmid DNA vaccination of mice.
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| description: |
A panel of 17 peptides spanniong the length of the PyCSP was used to map epitope specificity of antibodies from CS.1/CFA and pCSP immunized mice. Peptide 14 was uniquely recognized by sera from mice immunized with CS.1/CFA. Although no anti-PyCSP response was elicited when mice tolerized as neonates with pCSP were immunized or boosted with that DNA vaccine as adults, neonatally tolerized mice were able to produce IgG anti-PyCSP antibodies when immunized with CS.1 protein emulsified in CFA as adults.
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| name: |
iedb
|
| homePage: |
http://www.iedb.org |
