Immunological Data Discovery Index
Immunological Data Discovery Index
| authorizations: |
registration not required
|
| accessURL: |
http://www.iedb.org/reference/1002859 |
| landingPage: |
http://www.iedb.org/assay/1341089 |
| type: |
Literature
|
| publicationVenue: |
J Clin Invest
|
| dates: |
1996
|
| study type: | b cell assays |
| subject species: | Plasmodium yoelii yoelii |
| fullName: |
G Mor
G Yamshchikov
M Sedegah
M
R Wang
R A Houghten
S Hoffman
D M Klinman
|
| method: |
ELISA
|
| name: |
Induction of neonatal tolerance by plasmid DNA vaccination of mice.
|
| description: |
A panel of 17 peptides spanning the length of the PyCSP was used to map epitope specificity of antibodies from CS.1/CFA and pCSP immunized mice. Peptide 14 was not recognized by sera from mice immunized by plasmid DNA encoding the CSP (pCSP). Although no anti-PyCSP response was elicited when mice tolerized as neonates with pCSP were immunized or boosted with that DNA vaccine as adults, neonatally tolerized mice were able to produce IgG anti-PyCSP antibodies when immunized with CS.1 protein emulsified in CFA as adults.
|
| name: |
iedb
|
| homePage: |
http://www.iedb.org |
