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Title: Reproducing the immune response against the Plasmodium vivax merozoite surface protein 1 with mimotopes selected from a phage-displayed peptide library.
identifier: 1341604
description:
epitope description:YSTEVR
host organism:Mus musculus
antibody name:D14-3
aggregation:
instance of dataset
availability:
available
primaryPublications: 8960114
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1002899
landingPage: http://www.iedb.org/assay/1341604
type:
Literature
publicationVenue:
Mol Immunol
dates:
1996
study type: b cell assays
subject species:
fullName:
C Demangel
P Lafaye
J C Mazie
method:
cross blocking
name:
Reproducing the immune response against the Plasmodium vivax merozoite surface protein 1 with mimotopes selected from a phage-displayed peptide library.
description:
This peptide mimics the epitope found in Mr 42000 C-terminal fragment of Plasmodium vivax merozoite surface protein 1 (PvMSP1) that is bound by the monoclonal antibody D14-3.
The mimotope inhibited the binding of monoclonal antibody D14-3 to Pv42 (the C-terminal fragment of Plasmodium vivax merozoite surface protein). As there is no sequence in Pv42 that is identical, it is deemed to mimic the epitope of D14-3 on Pv42.

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