Immunological Data Discovery Index
Advanced Search
  1. << Go Back
Title: Evidence for diversity of Plasmodium falciparum sporozoite surface antigens derived from analysis of antibodies elicited in humans.
identifier: 1341863
description:
epitope description:NANPNANPNANP
antigen name:Circumsporozoite (CS) protein
host organism:Mus musculus
antibody name:NFS1, NFS2
aggregation:
instance of dataset
availability:
available
primaryPublications: 1696936
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1002916
landingPage: http://www.iedb.org/assay/1341863
type:
Literature
publicationVenue:
Infect Immun
dates:
1990
study type: b cell assays
subject species: Plasmodium falciparum
fullName:
B Galey
P Druilhe
I Ploton
C Desgranges
A Asavanich
T Harinasuta
C Marchand
K Brahimi
Y Charoenvit
C Paul
method:
antigen inhibition
name:
Evidence for diversity of Plasmodium falciparum sporozoite surface antigens derived from analysis of antibodies elicited in humans.
description:
The circumsporozoite protein contains multiple tandem repeats of the sequence NANP.
The epitope inhibited the binding of MAbs NFS1 (IgG1) and NFS2 (IgG2a) to P. falciparum sporozoites as detected by indirect immunofluorescence. The recombinant peptide R32tet32, composed of 30 NANP and 2 NVDP repeats, also inhibited binding of the MAbs.

Feedback?

If you are having problems using our tools, or if you would just like to send us some feedback, please post your questions on Feedback.

ImmuneData is supported by the NIAID, Grant HHSN272201700019C. Privacy

ImmuneData is developed by TechWave International, Inc. and UT Health Science Center at Houston