Heat shock response of Babesia divergens and identification of the hsp70 as an immunodominant early antigen during ox, gerbil and human babesiosis.

Title:

Heat shock response of Babesia divergens and identification of the hsp70 as an immunodominant early antigen during ox, gerbil and human babesiosis.

Dataset

identifier:	1342411
description:	epitope description:MPGGMPGGMPGGMPGG antigen name:Heat shock 70 kDa protein host organism:Oryctolagus cuniculus antibody name:anti-R (repeat)
aggregation:	instance of dataset
availability:	available
primaryPublications:	1756315

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1002935
landingPage:	http://www.iedb.org/assay/1342411

Publication

type:	Literature
publicationVenue:	Biol Cell
dates:	1991

Dimension

study type:	b cell assays
subject species:	Plasmodium falciparum

Person

fullName:	B Carcy E Pré cigout A Valentin A Gorenflot R T Reese J Schré vel

Data Type

method:	immunoprecipitation

Study

name:	Heat shock response of Babesia divergens and identification of the hsp70 as an immunodominant early antigen during ox, gerbil and human babesiosis.
description:	The sequence is described in the reference cited: Richman et al. (1989) J. Immunol. 143: 285-293. The sequence is from the P. falciparum hsp75 molecule, a member of the heat shock protein 70 family. Sera from rabbits immunized with the epitope immunoprecipitated a single protein of M_r 70,000, designated hsp70, from 35S-methionine labelled B. divergens Rouen1987 polypeptides. The antisera also recognized hsp70 on Western blots of different human (LeMans 1988 and Rouen1987) or bovine isolates (Munich 1987, Taylor Y5, Weybridge 8843, and 7107 B) of B. divergens from various geograhic origins. The authors conclude that B. divergens hsp70 is highly conserved.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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