Epitopes of the human malaria parasite P. falciparum carried on the surface of HBsAg particles elicit an immune response against the parasite.

Title:

Epitopes of the human malaria parasite P. falciparum carried on the surface of HBsAg particles elicit an immune response against the parasite.

identifier:	1346615
description:	epitope description:IEESKKTIDKNKNATKEEEKKKLYQA antigen name:Merozoite surface protein 1 host organism:Oryctolagus cuniculus
aggregation:	instance of dataset
availability:	available
primaryPublications:	1716808

study type:	b cell assays
subject species:	Plasmodium falciparum K1

fullName:	A von Brunn K Frü h H M Mü ller H W Zentgraf H Bujard

method:	ELISA

name:	Epitopes of the human malaria parasite P. falciparum carried on the surface of HBsAg particles elicit an immune response against the parasite.
description:	This putative B cell epitope was selected by computer algorithms as having a high antigenic profile. It is located in the conserved part of the protein that is recognized by human antibodies as well as by human CD4+ T cells. Rabbits were immunized with vaccinia virus expressing a recombinant fusion protein where the epitope is inserted in the second hydrophilic domain of Hepatitis B surface Ag. The antisera is shown to recognize a peptide-CAT (chorampenicol acetyltransferase) fusion protein.

name:	iedb
homePage:	http://www.iedb.org

If you are having problems using our tools, or if you would just like to send us some feedback, please post your questions on Feedback.