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identifier: 1345675
description:
epitope description:NANPNANPNANP
antigen name:Circumsporozoite (CS) protein
host organism:Mus musculus BALB/c
antibody name:A24, A5, A8, MB4, A1/4, A5/4, A2/1, A1/6, A1/1, A5/1, A4/7, A2/6, C4/6, A5/5
aggregation:
instance of dataset
availability:
available
primaryPublications: 8099745
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1002781
landingPage: http://www.iedb.org/assay/1345675
type:
Literature
publicationVenue:
Philos Trans R Soc Lond B Biol Sci
dates:
1993
study type: b cell assays
subject species: Plasmodium falciparum
fullName:
H M Etlinger
A Trzeciak
method:
immuno staining
name:
Towards a synthetic malaria vaccine: cyclization of a peptide eliminates the production of parasite-unreactive antibody.
description:
Epitope specific monoclonal antibodies generated through immunization of mice with either (linear(NANP)3)19 or (circular(NANP)3)19 recognized P. falciparum sporozoites. Immunization with the circular epitope construct resulted in greater recognition than immunization with the linear construct. Antibodies were of IgG1, IgG2a, IgG2b, and IgM isotypes.

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