Immunological Data Discovery Index
Immunological Data Discovery Index
| authorizations: |
registration not required
|
| accessURL: |
http://www.iedb.org/reference/1003160 |
| landingPage: |
http://www.iedb.org/assay/1349471 |
| type: |
Literature
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| publicationVenue: |
Mol Immunol
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| dates: |
1987
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| study type: | b cell assays |
| subject species: | Hepatitis B virus subtype adw2 |
| fullName: |
A R Neurath
S B Kent
P Adamowicz
M M Riottot
P Price
N Strick
K Parker
M A Petit
A Budkowska
M Girard
et al.
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| method: |
antigen inhibition
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| name: |
Immunological cross-reactivity between preS2 sequences of the hepatitis B virus envelope proteins corresponding to serological subtypes adw2 and ayw.
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| description: |
The epitope was capable of out-competing epitope-specific rabbit antisera for binding to the preS2(ayw)-beta-gal probe. Antibodies generated against the epitope had a much less narrow subtype specificity than the HBsAg antisera or the McAb F376. A further analysis using a double-antibody assay confirmed that the epitope-specific sera were broadly subtype-cross-reactive. A Gly-Gly-Cys-amide was added to the C terminus.
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| name: |
iedb
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| homePage: |
http://www.iedb.org |
