Recombinant chimeric proteins generated from conserved regions of Plasmodium falciparum merozoite surface protein 2 generate antiparasite humoral responses in mice.

Title:

Recombinant chimeric proteins generated from conserved regions of Plasmodium falciparum merozoite surface protein 2 generate antiparasite humoral responses in mice.

Dataset

identifier:	1349055
description:	epitope description:YNMSIRRS antigen name:Merozoite surface antigen 2 host organism:Mus musculus
aggregation:	instance of dataset
availability:	available
primaryPublications:	10792760

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1002696
landingPage:	http://www.iedb.org/assay/1349055

Publication

type:	Literature
publicationVenue:	Parasite Immunol
dates:	2000

Dimension

study type:	b cell assays
subject species:	Plasmodium falciparum 3D7

Person

fullName:	N Lawrence A Stowers V Mann D A Saul

Data Type

method:	ELISA

Study

name:	Recombinant chimeric proteins generated from conserved regions of Plasmodium falciparum merozoite surface protein 2 generate antiparasite humoral responses in mice.
description:	Antisera from mice (two of each B10.BR, Balb/C and Quackenbush strains) immunized with recombinant chimeric NC protein were tested for binding against overlapping octapeptides to identify positive regions. Similar results were obtained with mice (one of each Balb/C and Quackenbush) immunized with recombinant chimeric 1624 malaria vaccine.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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