T and B cell responses of Plasmodium falciparum malaria-immune individuals to synthetic peptides corresponding to sequences in different regions of the P. falciparum antigen Pf155/RESA.

Title:

T and B cell responses of Plasmodium falciparum malaria-immune individuals to synthetic peptides corresponding to sequences in different regions of the P. falciparum antigen Pf155/RESA.

Dataset

identifier:	1349132
description:	epitope description:TVAEEHVEEPTVAEE antigen name:DNAJ protein, putative host organism:Homo sapiens
aggregation:	instance of dataset
availability:	available
primaryPublications:	2478632

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1002879
landingPage:	http://www.iedb.org/assay/1349132

Publication

type:	Literature
publicationVenue:	J Immunol
dates:	1989

Dimension

study type:	b cell assays
subject species:	Plasmodium falciparum

Person

fullName:	M E M Riley H Perlmann G Andersson A Larsson R W Snow S J Allen R A Houghten O Olerup B M Greenwood

Data Type

method:	ELISA

Study

name:	T and B cell responses of Plasmodium falciparum malaria-immune individuals to synthetic peptides corresponding to sequences in different regions of the P. falciparum antigen Pf155/RESA.
description:	Antibody responses to the epitope tended to decrease after a period with no P. falciparum transmission (dry season), whereas T cell responses to the epitope were shown to persist, suggesting differences in the requirements of boosting at the T and B cell levels, respectively.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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