Immunological Data Discovery Index
Immunological Data Discovery Index
| identifier: | 1352136 |
| description: |
epitope description:3,6-dideoxy-4-C-(1,3-dimethoxy-4,5,6,7-tetrahydroxyheptyl)-alpha-D-xylo-hexp-(1->3)-beta-L-Xylp
antigen name:lipooligosaccharide
host organism:Oryctolagus cuniculus Fauve de Bourgogne
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| aggregation: |
instance of dataset
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| availability: |
available
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| primaryPublications: |
7496145 |
| authorizations: |
registration not required
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| accessURL: |
http://www.iedb.org/reference/1003333 |
| landingPage: |
http://www.iedb.org/assay/1352136 |
| type: |
Literature
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| publicationVenue: |
Glycoconj J
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| dates: |
1995
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| study type: | b cell assays |
| subject species: | Mycobacterium gastri W471 |
| fullName: |
M Gilleron
G Puzo
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| method: |
antigen inhibition
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| name: |
Lipooligosaccharidic antigens from Mycobacterium kansasii and Mycobacterium gastri.
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| description: |
The terminal disaccharide of LOS-III is defined as the epitopic region for anti-LOS-III Abs. Its name is 3,6-dideoxy-4-C-(1,3-dimethoxy-4,5,6,7-tetrahydroxy-heptyl)-a-xylo-hexp-(1-3)-b-L-Xylp. The Lipooligosaccharide III (LOS III) is the source of the epitope. It is the major LOS species found in M.gastri. Its complete oligosaccharide part is 3,6-dideoxy-4-C-(1,3-dimethoxy-4,5,6,7-tetrahydroxy-heptyl)-a-xylo-hexp-(1-3)-[b-L-Xylp-(1-4)]6-3-O-Me-Rhap-(1-3)-b-D-Galp-(1-3)-b-D-Glcp-(1-4)-a-D-Glcp-(1-1)-a-D-Glcp. The lipid chains are linked to the 2 proximal 1-1 linked Glc residues.
Anti-M.gastri antibodies are inhibited in the binding to solid-pahse LOS-III by the soluble LOS-III. Based on the reactivity to other LOS molecules, the involvement of the epitopic residues is deduced.
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| name: |
iedb
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| homePage: |
http://www.iedb.org |
