Immunological Data Discovery Index
Immunological Data Discovery Index
| Title: | Presentation of two epitopes of the preS2 region of hepatitis B virus on live recombinant bacteria. |
| authorizations: |
registration not required
|
| accessURL: |
http://www.iedb.org/reference/1003182 |
| landingPage: |
http://www.iedb.org/assay/1349527 |
| type: |
Literature
|
| publicationVenue: |
J Immunol
|
| dates: |
1987
|
| study type: | b cell assays |
| subject species: | Hepatitis B virus subtype ayw |
| fullName: |
A Charbit
E Sobczak
M L Michel
A Molla
P Tiollais
M Hofnung
|
| method: |
ELISA
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| name: |
Presentation of two epitopes of the preS2 region of hepatitis B virus on live recombinant bacteria.
|
| description: |
The sequence is from scheme 1 and the reference cited: Tiollais et al. (1985) Nature 317: 489.
Two of four rabbits immunized with bacteria expressing the LamB-preS2-A hybrid protein, which contains residues 132-145 (QDPRVRGLYFPAGG) of the epitope inserted in bacterial LamB protein, produced high titer antibodies to the epitope after 50 days and four immunizations.
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| name: |
iedb
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| homePage: |
http://www.iedb.org |