| authorizations: |
registration not required
|
| accessURL: |
http://www.iedb.org/reference/1003094 |
| landingPage: |
http://www.iedb.org/assay/1349538 |
| type: |
Literature
|
| publicationVenue: |
Infect Immun
|
| dates: |
2005
|
| study type: | b cell assays |
| subject species: | Plasmodium falciparum |
| fullName: |
Kim Brustoski
Martin Kramer
Ulrike Mö
ller
Peter G Kremsner
Adrian J F Luty
|
| method: |
ELISA
|
| name: |
Neonatal and maternal immunological responses to conserved epitopes within the DBL-gamma3 chondroitin sulfate A-binding domain of Plasmodium falciparum erythrocyte membrane protein 1.
|
| description: |
This sequence is confirmed by the authors to be used in the assays, even when the sequence presented in the manuscript has an extra D residues listed at position 7.
The proportion of cord blood samples positive for IgM specificity towards this peptide is higher from neonates whose mothers were treated for P.falciparum infection or that had P.falciparum-positive placental tissue than from mothers exposed but with negative placental infection. The mothers of all 3 groups also had levels of IgM, and IgG, to this peptide above non-exposed controls.
|
| name: |
iedb
|
| homePage: |
http://www.iedb.org |