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identifier: 1349538
description:
epitope description:DICLGTDISVKQGDV
antigen name:Erythrocyte membrane protein 1, PfEMP1 (UniProt:Q8I220)
host organism:Homo sapiens
aggregation:
instance of dataset
availability:
available
primaryPublications: 16299291
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1003094
landingPage: http://www.iedb.org/assay/1349538
type:
Literature
publicationVenue:
Infect Immun
dates:
2005
study type: b cell assays
subject species: Plasmodium falciparum
fullName:
Kim Brustoski
Martin Kramer
Ulrike Mö
ller
Peter G Kremsner
Adrian J F Luty
method:
ELISA
name:
Neonatal and maternal immunological responses to conserved epitopes within the DBL-gamma3 chondroitin sulfate A-binding domain of Plasmodium falciparum erythrocyte membrane protein 1.
description:
This sequence is confirmed by the authors to be used in the assays, even when the sequence presented in the manuscript has an extra D residues listed at position 7.
The proportion of cord blood samples positive for IgM specificity towards this peptide is higher from neonates whose mothers were treated for P.falciparum infection or that had P.falciparum-positive placental tissue than from mothers exposed but with negative placental infection. The mothers of all 3 groups also had levels of IgM, and IgG, to this peptide above non-exposed controls.

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