A monoclonal antibody against the X protein of hepatitis B virus: fine mapping of its epitope and application in a quantitative ELISA of the X protein in sera of hepatitis B patients.

Title:

A monoclonal antibody against the X protein of hepatitis B virus: fine mapping of its epitope and application in a quantitative ELISA of the X protein in sera of hepatitis B patients.

Dataset

identifier:	1349738
description:	epitope description:HKRTLGL antigen name:Protein X host organism:Mus musculus BALB/c antibody name:B-8/2/8
aggregation:	instance of dataset
availability:	available
primaryPublications:	9627056

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1003199
landingPage:	http://www.iedb.org/assay/1349738

Publication

type:	Literature
publicationVenue:	Hybridoma
dates:	1998

Dimension

study type:	b cell assays
subject species:	Hepatitis B virus

Person

fullName:	V Kumar N Jayasuryan H Reddi D Sahal S K Panda

Data Type

method:	ELISA

Study

name:	A monoclonal antibody against the X protein of hepatitis B virus: fine mapping of its epitope and application in a quantitative ELISA of the X protein in sera of hepatitis B patients.
description:	Epitope mapping with the monoclonal antibody was performed with deletion mutants of the Hbx protein, followed by scanning of overlapping octameric peptides spanning the deduced reactive region of the protein. Further, binding of the monoclonal antibody to the the most reactive octapeptide (HKRTLGLP) was selectively reduced in the presence of the deduced heptapeptide epitope (HKRTLGL).

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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