Immune response to the pre-S(1) region of the hepatitis B surface antigen (HBsAg): a pre-S(1)-specific T cell response can bypass nonresponsiveness to the pre-S(2) and S regions of HBsAg.

Title:

Immune response to the pre-S(1) region of the hepatitis B surface antigen (HBsAg): a pre-S(1)-specific T cell response can bypass nonresponsiveness to the pre-S(2) and S regions of HBsAg.

Dataset

identifier:	1350393
description:	epitope description:PAFGANSNNPDWDFNPVKDDWP antigen name:Large envelope protein host organism:Mus musculus
aggregation:	instance of dataset
availability:	available
primaryPublications:	2423607

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1003213
landingPage:	http://www.iedb.org/assay/1350393

Publication

type:	Literature
publicationVenue:	J Immunol
dates:	1986

Dimension

study type:	b cell assays
subject species:	Hepatitis B virus subtype adw2

Person

fullName:	D R Milich A McLachlan F V Chisari S B Kent G B Thorton

Data Type

method:	ELISA

Study

name:	Immune response to the pre-S(1) region of the hepatitis B surface antigen (HBsAg): a pre-S(1)-specific T cell response can bypass nonresponsiveness to the pre-S(2) and S regions of HBsAg.
description:	The strength of Ab responses from mice immunized with HBsAg/p39 (including S, pre-S1 and pre-S2) against the epitope was: B10.D2 > B10.M > B10.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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