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Title: Vaccine engineering: enhancement of immunogenicity of synthetic peptide vaccines related to hepatitis in chemically defined models consisting of T- and B-cell epitopes.
identifier: 1350848
description:
epitope description:TKPTDGN
antigen name:Large envelope protein
host organism:Oryctolagus cuniculus New Zealand White
aggregation:
instance of dataset
availability:
available
primaryPublications: 2480595
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1003226
landingPage: http://www.iedb.org/assay/1350848
type:
Literature
publicationVenue:
Proc Natl Acad Sci U S A
dates:
1989
study type: b cell assays
subject species: Hepatitis B virus
fullName:
J P Tam
Y A Lu
method:
ELISA
name:
Vaccine engineering: enhancement of immunogenicity of synthetic peptide vaccines related to hepatitis in chemically defined models consisting of T- and B-cell epitopes.
description:
Different models were designed to produce MAPs containing the epitope. In the heterologous branching model, 4 copies of two different antigens were attached to the same octabranching MAP to give a diepitope MAP with a design of alternating antigens. For comparison, the dimer was also tested resulting in similar response.

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