Immunological Data Discovery Index
Advanced Search
  1. << Go Back
Title: Vaccine engineering: enhancement of immunogenicity of synthetic peptide vaccines related to hepatitis in chemically defined models consisting of T- and B-cell epitopes.
identifier: 1350850
description:
epitope description:TKPTDGN
antigen name:Large envelope protein
host organism:Oryctolagus cuniculus New Zealand White
aggregation:
instance of dataset
availability:
available
primaryPublications: 2480595
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1003226
landingPage: http://www.iedb.org/assay/1350850
type:
Literature
publicationVenue:
Proc Natl Acad Sci U S A
dates:
1989
study type: b cell assays
subject species: Hepatitis B virus
fullName:
J P Tam
Y A Lu
method:
ELISA
name:
Vaccine engineering: enhancement of immunogenicity of synthetic peptide vaccines related to hepatitis in chemically defined models consisting of T- and B-cell epitopes.
description:
Different models were designed to produce MAPs containing the epitope. In the heterologous branching model, 4 copies of two different antigens were attached to the same octabranching MAP to give a diepitope MAP with a design of alternating antigens. For comparison, the dimer was also tested resulting in a better response.

Feedback?

If you are having problems using our tools, or if you would just like to send us some feedback, please post your questions on Feedback.

ImmuneData is supported by the NIAID, Grant HHSN272201700019C. Privacy

ImmuneData is developed by TechWave International, Inc. and UT Health Science Center at Houston