| authorizations: |
registration not required
|
| accessURL: |
http://www.iedb.org/reference/1003226 |
| landingPage: |
http://www.iedb.org/assay/1350799 |
| type: |
Literature
|
| publicationVenue: |
Proc Natl Acad Sci U S A
|
| dates: |
1989
|
| study type: | b cell assays |
| subject species: | Hepatitis B virus |
| fullName: |
J P Tam
Y A Lu
|
| method: |
ELISA
|
| name: |
Vaccine engineering: enhancement of immunogenicity of synthetic peptide vaccines related to hepatitis in chemically defined models consisting of T- and B-cell epitopes.
|
| description: |
Different models were designed to produce MAPs containing the epitope. In the homologous branching model, the antigen was branched homologously to give 8 copies of dendritic forms of antigens attached to the core or a homomeric dimer of the MAP was produced by the removal of the protecting group. Also, a heterodimer containing a diepitope MAP was tested resulting in the best response.
|
| name: |
iedb
|
| homePage: |
http://www.iedb.org |