Immunological Data Discovery Index
Immunological Data Discovery Index
| authorizations: |
registration not required
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| accessURL: |
http://www.iedb.org/reference/1003310 |
| landingPage: |
http://www.iedb.org/assay/1352571 |
| type: |
Literature
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| publicationVenue: |
Infect Immun
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| dates: |
1994
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| study type: | b cell assays |
| subject species: | Mycobacterium leprae |
| fullName: |
S Singh
P J Jenner
N P Narayan
G Ramu
M J Colston
H K Prasad
I Nath
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| method: |
ELISA
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| name: |
Critical residues of the Mycobacterium leprae LSR recombinant protein discriminate clinical activity in erythema nodosum leprosum reactions.
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| description: |
Sera from patients with erythema nodosum leprosum (ENL) reactions and other leprosy patients were studied for binding to the epitope. Three distinct regions were identified, GVTY, NAA and RGD, which were important for antibody recognition and for the discrimination of clinically silent and active ENL reactions. Antibodies to the NAA were found only in patients undergoing active reaction, whereas antibodies to the other two sites were found in both groups of patients.
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| name: |
iedb
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| homePage: |
http://www.iedb.org |
