Definition of the primary structure of hepatitis B virus (HBV) pre-S hepatocyte binding domain using random peptide libraries.

Title:

Definition of the primary structure of hepatitis B virus (HBV) pre-S hepatocyte binding domain using random peptide libraries.

identifier:	1355573
description:	epitope description:PQAMQWNSTAFH antigen name:Large envelope protein host organism:Mus musculus antibody name:Q19/10
aggregation:	instance of dataset
availability:	available
primaryPublications:	9356343

study type:	b cell assays
subject species:	Hepatitis B virus subtype adw2

fullName:	F D'Mello C D Partidos M W Steward C R Howard

method:	ELISA

name:	Definition of the primary structure of hepatitis B virus (HBV) pre-S hepatocyte binding domain using random peptide libraries.
description:	This sequence is recognized in a PEPSCAN analysis by a mAb that also recognized a different peptide of Pre-S2 region of HBsAg, residues 131-142. Pepscan analysis of overlapping peptides covering the pre-S region of HBsAg adw2 allowed for the determination of this region as involved in the epitope recognized by a mAb raised against subtype adw virions.

name:	iedb
homePage:	http://www.iedb.org

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