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identifier: 1354822
description:
epitope description:TNPVLRS
host organism:Mus musculus
antibody name:BX-182
aggregation:
instance of dataset
availability:
available
primaryPublications: 16757558
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1003519
landingPage: http://www.iedb.org/assay/1354822
type:
Literature
publicationVenue:
Proc Natl Acad Sci U S A
dates:
2006
study type: b cell assays
subject species:
fullName:
Pei Zhang
Mei-Ying W Yu
Richard Venable
Harvey J Alter
J Wai-Kou Shih
method:
phage display
name:
Neutralization epitope responsible for the hepatitis B virus subtype-specific protection in chimpanzees.
description:
A random phage library was panned with the monoclonal antibody, and 9 of 10 sequenced clones were found to display this peptide. Both Val and Pro residues and, to some extent, the Ser residue, were found to be essential components for antibody binding.

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