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Title: Monoclonal anti-gametocyte antibodies identify an antigen present in all blood stages of Plasmodium falciparum.
identifier: 1356030
description:
epitope description:EENVEENVEENVEENV
antigen name:DNAJ protein, putative
host organism:Mus musculus
antibody name:9B11
aggregation:
instance of dataset
availability:
available
primaryPublications: 3526145
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1003521
landingPage: http://www.iedb.org/assay/1356030
type:
Literature
publicationVenue:
Mol Biochem Parasitol
dates:
1986
study type: b cell assays
subject species: Plasmodium falciparum
fullName:
A Masuda
F Zavala
V Nussenzweig
R S Nussenzweig
method:
immuno staining
name:
Monoclonal anti-gametocyte antibodies identify an antigen present in all blood stages of Plasmodium falciparum.
description:
The ring-infested erythrocyte surface antigen (RESA) contains multiple repeats of sequence EENV.
The epitope-specific mAb 9B11 bound to air dried or fixed and dried preparations of P. falciparum infected RBCs. MAb 9B11 recognized various sexual stages of P. falciparum, including ring-infected erythrocytes, gametocytes, trophozoites, and schizonts. MAb 9B11 recognized RBCs infected with P. falciparum isolates (7G8, 1EC51, HB-3, W-2, T-4, FC-27, D-6, FCR-3, LE-5, and I-2) from different geographic areas (South and Central America, Asia, and Africa).

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