Cryptic properties of a cluster of dominant flavivirus cross-reactive antigenic sites. | ImmuneData Discovery Index

Immunological Data Discovery Index

Immunological Data Discovery Index

Title:

Cryptic properties of a cluster of dominant flavivirus cross-reactive antigenic sites.

Dataset

identifier:	1369654
description:	epitope description:G104, G106, E126, W231 antigen name:Genome polyprotein host organism:Mus musculus antibody name:6B6C1
aggregation:	instance of dataset
availability:	available
primaryPublications:	16973559

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1003578
landingPage:	http://www.iedb.org/assay/1369654

Publication

type:	Literature
publicationVenue:	J Virol
dates:	2006

Dimension

study type:	b cell assays
subject species:	Dengue virus 2

Person

fullName:	Karin Stiasny Stefan Kiermayr Heidemarie Holzmann Franz X Heinz

Data Type

method:	biological activity

Study

name:	Cryptic properties of a cluster of dominant flavivirus cross-reactive antigenic sites.
description:	The epitope was identified previously (J Virol 2004 78:13975-13986) following mutational analysis of the E protein of Dengue virus. DENV-specific mAb 6B6C1 was found to be broadly cross-reactive against all flaviruses tested (TBEV, JEV, WNV and DENV).

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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