Characterization of complex B cell epitopes on woodchuck hepatitis virus surface antigens by using plasmids encoding chimeric proteins and DNA immunization.

Title:

Characterization of complex B cell epitopes on woodchuck hepatitis virus surface antigens by using plasmids encoding chimeric proteins and DNA immunization.

Dataset

identifier:	1357357
description:	epitope description:CRQCTISYQDMYTPPYCCCLKPTAGNC antigen name:Large envelope protein host organism:Capra hircus
aggregation:	instance of dataset
availability:	available
primaryPublications:	12009876

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1003380
landingPage:	http://www.iedb.org/assay/1357357

Publication

type:	Literature
publicationVenue:	Virology
dates:	2002

Dimension

study type:	b cell assays
subject species:	Woodchuck hepatitis virus

Person

fullName:	Xin Zheng Reinhold Schirmbeck Gero Hilken Jennifer A Waters Dongliang Yang Jö rg Reimann Michael Roggendorf Mengji Lu

Data Type

method:	immuno staining

Study

name:	Characterization of complex B cell epitopes on woodchuck hepatitis virus surface antigens by using plasmids encoding chimeric proteins and DNA immunization.
description:	No cross reactivity at the recognition of this epitope is found in anti-HBsAg antisera. Mutations of the epitope sequence (L136T and A140N) mimicking the sequence of the HBsAg a determinant second loop allowed for a weak anti-HBsAg responses.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

Feedback?

If you are having problems using our tools, or if you would just like to send us some feedback, please post your questions on Feedback.

Related Publications

Feedback?