Immunological Data Discovery Index
Immunological Data Discovery Index
| authorizations: |
registration not required
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| accessURL: |
http://www.iedb.org/reference/1003612 |
| landingPage: |
http://www.iedb.org/assay/1368142 |
| type: |
Literature
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| publicationVenue: |
J Med Virol
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| dates: |
2000
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| study type: | b cell assays |
| subject species: | Hepatitis B virus subtype adw2 |
| fullName: |
J S Moynihan
F I D'Mello
C R Howard
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| method: |
antigen inhibition
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| name: |
48-mer synthetic peptide analogue of the hepatitis B virus ""a"" determinant induces an anti-HBs antibody response after a single injection.
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| description: |
Peptide bound to the solid phase competed with free HBsAg for binding to polyclonal anti-HBs antisera, thus demonstrating that the peptide displays in vitro some of the epitopes present on the native HBsAg.The peptide is 48 amino acids long, and encompasses the entire HBV 'a' determinant. This region includes immunodominant B cell epitopes between amino acids 139-145 and a known T-helper epitope around amino acids 164-167.
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| name: |
iedb
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| homePage: |
http://www.iedb.org |
