Identification of hepatitis A virus mimotopes by phage display, antigenicity and immunogenicity. | ImmuneData Discovery Index

Immunological Data Discovery Index

Immunological Data Discovery Index

Title:

Identification of hepatitis A virus mimotopes by phage display, antigenicity and immunogenicity.

Dataset

identifier:	1368180
description:	epitope description:SHSQLGPPVGGPP host organism:Mus musculus BALB/c antibody name:anti-HAV
aggregation:	instance of dataset
availability:	available
primaryPublications:	17129616

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1003558
landingPage:	http://www.iedb.org/assay/1368180

Publication

type:	Literature
publicationVenue:	J Virol Methods
dates:	2007

Dimension

study type:	b cell assays
subject species:

Person

fullName:	Osmany G Larralde Raiza Martinez Frank Camacho Nevis Amin Alicia Aguilar Arturo Talavera David I Stott Ela M Perez

Data Type

method:	ELISA

Study

name:	Identification of hepatitis A virus mimotopes by phage display, antigenicity and immunogenicity.
description:	The mimotope was selected using serum from a convalescent viral hepatitis A patient but has no sequence homology to hepatitis A virus VP1 or VP3 capsid proteins. Mice immunized with the phage clone displaying the epitope produced a strong antibody response to HAV by day 42. The authors conclude that the epitope can adopt a conformation similar to a viral protein region.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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