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Title: Influences of glycosylation on antigenicity, immunogenicity, and protective efficacy of ebola virus GP DNA vaccines.
identifier: 1368408
description:
epitope description:GLICGLRQLANETTQALQ
antigen name:Envelope glycoprotein
host organism:Mus musculus BALB/c
aggregation:
instance of dataset
availability:
available
primaryPublications: 17151111
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1003552
landingPage: http://www.iedb.org/assay/1368408
type:
Literature
publicationVenue:
J Virol
dates:
2007
study type: b cell assays
subject species: Ebola virus - Mayinga, Zaire, 1976
fullName:
William Dowling
Elizabeth Thompson
Catherine Badger
Jenny L Mellquist
Aura R Garrison
Jeffery M Smith
Jason Paragas
Robert J Hogan
Connie Schmaljohn
method:
ELISA
name:
Influences of glycosylation on antigenicity, immunogenicity, and protective efficacy of ebola virus GP DNA vaccines.
description:
Overlapping 18-mer peptides in a pool (4 peptides each) were tested with ELISA and deconvolved. Mice immunized with N-glycosylation site mutants or mucin deletion constructs exhibited different antibody responsive patterns.

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