Aldehyde modification of peptide immunogen enhances protein-reactive antibody response to toxic shock syndrome toxin-1.

Title:

Aldehyde modification of peptide immunogen enhances protein-reactive antibody response to toxic shock syndrome toxin-1.

identifier:	1369713
description:	epitope description:SPAFTKGEKVDLN antigen name:UniProt:D6SEW7 host organism:Oryctolagus cuniculus New Zealand White
aggregation:	instance of dataset
availability:	available
primaryPublications:	17131300

study type:	b cell assays
subject species:	Staphylococcus aureus

fullName:	Alfonso Bavoso Angela Ostuni Jolanda De Vendel Francesco Pollaro Francesca Armentano Thomas Knight Sudesh Makker Alfonso Tramontano

method:	ELISA

name:	Aldehyde modification of peptide immunogen enhances protein-reactive antibody response to toxic shock syndrome toxin-1.
description:	Carbonyl tags were introduced to the immunizing peptide by Amadori reaction with glycolaldehyde. Aldehyde modification augmented the response to TSST-1. This reactivity of the anti-peptide antisera with TSST-1 was negative in Western blot analysis.

name:	iedb
homePage:	http://www.iedb.org

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