Immunological Data Discovery Index
Immunological Data Discovery Index
| Title: | Locations of antibody binding sites within conserved regions of the hepatitis C virus core protein. |
| authorizations: |
registration not required
|
| accessURL: |
http://www.iedb.org/reference/1002682 |
| landingPage: |
http://www.iedb.org/assay/1369949 |
| type: |
Literature
|
| publicationVenue: |
J Med Virol
|
| dates: |
1994
|
| study type: | b cell assays |
| subject species: | Hepatitis C virus |
| fullName: |
M Sä
llberg
P Pumpen
Z X Zhang
P Lundholm
I Gusars
U Rudé
n
B Wahren
L O Magnius
|
| method: |
ELISA
|
| name: |
Locations of antibody binding sites within conserved regions of the hepatitis C virus core protein.
|
| description: |
The amino acid sequence of the HCV core was derived from the sequence of a U.S. HCV clone.
Fine mapping of human reactivities to HCV core protein, using omission peptide analogs covering large regions of the protein (11-28, 21-38, 1-38, and 51-98) between residues 1-118, was used to identified six antibody binding sites. All binding sites were found to be mainly hydrophilic, except for the 29-34 site.
|
| name: |
iedb
|
| homePage: |
http://www.iedb.org |