Vaccination with prion peptide-displaying papillomavirus-like particles induces autoantibodies to normal prion protein that interfere with pathologic prion protein production in infected cells.

Title:

Vaccination with prion peptide-displaying papillomavirus-like particles induces autoantibodies to normal prion protein that interfere with pathologic prion protein production in infected cells.

Dataset

identifier:	1370146
description:	epitope description:DWEDRYYRE antigen name:Major prion protein host organism:Rattus norvegicus Lewis
aggregation:	instance of dataset
availability:	available
primaryPublications:	17313482

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1003619
landingPage:	http://www.iedb.org/assay/1370146

Publication

type:	Literature
publicationVenue:	FEBS J
dates:	2007

Dimension

study type:	b cell assays
subject species:	Mus musculus

Person

fullName:	Alessandra Handisurya Sabine Gilch Dorian Winter Saeed Shafti-Keramat Dieter Maurer Hermann M Schä tzl Reinhard Kirnbauer

Data Type

method:	ELISA

Study

name:	Vaccination with prion peptide-displaying papillomavirus-like particles induces autoantibodies to normal prion protein that interfere with pathologic prion protein production in infected cells.
description:	Animals immunized with the epitope recognized the epitope by ELISA, and pre-adsorption with the epitope led to decreased binding.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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