Immunological characterization of abnormal prion protein from atypical scrapie cases in sheep using a panel of monoclonal antibodies.

Title:

Immunological characterization of abnormal prion protein from atypical scrapie cases in sheep using a panel of monoclonal antibodies.

identifier:	1370400
description:	epitope description:WGQGGSHSQW antigen name:Major prion protein host organism:Mus musculus antibody name:ICSM35
aggregation:	instance of dataset
availability:	available
primaryPublications:	17098989

study type:	b cell assays
subject species:	Ovis aries

fullName:	Anja Gretzschel Anne Buschmann Jan Langeveld Martin H Groschup

method:	western blot

name:	Immunological characterization of abnormal prion protein from atypical scrapie cases in sheep using a panel of monoclonal antibodies.
description:	Epitope specific mAb ICSM35 detected classical scrapie, atypical scrapie including the 11 kDa fragment and the BSE isolate, both before and after PK digestion. Species tested and recognized by this mAb include sheep, cattle, mouse, hamster and human PrP.

name:	iedb
homePage:	http://www.iedb.org

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