Immunological characterization of abnormal prion protein from atypical scrapie cases in sheep using a panel of monoclonal antibodies.

Title:

Immunological characterization of abnormal prion protein from atypical scrapie cases in sheep using a panel of monoclonal antibodies.

identifier:	1370406
description:	epitope description:YEDRYYRENM antigen name:Major prion protein host organism:Mus musculus antibody name:6H4
aggregation:	instance of dataset
availability:	available
primaryPublications:	17098989

study type:	b cell assays
subject species:	Ovis aries

fullName:	Anja Gretzschel Anne Buschmann Jan Langeveld Martin H Groschup

method:	western blot

name:	Immunological characterization of abnormal prion protein from atypical scrapie cases in sheep using a panel of monoclonal antibodies.
description:	Epitope specific mAb 6H4 detected classical scrapie, of the BSE isolate and the upper fragments of atypical scrapie before PK digestion. However, after PK digestion, the atypical scrapie cases were no longer detected. Species tested and recognized by this mAb include sheep, cattle, mouse, hamster, mink and human PrP.

name:	iedb
homePage:	http://www.iedb.org

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