Immunogenicity and antigenicity of chimeric picornaviruses which express hepatitis A virus (HAV) peptide sequences: evidence for a neutralization domain near the amino terminus of VP1 of HAV.

Title:

Immunogenicity and antigenicity of chimeric picornaviruses which express hepatitis A virus (HAV) peptide sequences: evidence for a neutralization domain near the amino terminus of VP1 of HAV.

Dataset

identifier:	1371076
description:	epitope description:NSNNKEYT antigen name:Genome polyprotein host organism:Cavia porcellus
aggregation:	instance of dataset
availability:	available
primaryPublications:	1314456

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1003717
landingPage:	http://www.iedb.org/assay/1371076

Publication

type:	Literature
publicationVenue:	Virology
dates:	1992

Dimension

study type:	b cell assays
subject species:	Hepatovirus A

Person

fullName:	S M Lemon W Barclay M Ferguson P Murphy L Jing K Burke D Wood K Katrak D Sangar P D Minor et al.

Data Type

method:	biological activity

Study

name:	Immunogenicity and antigenicity of chimeric picornaviruses which express hepatitis A virus (HAV) peptide sequences: evidence for a neutralization domain near the amino terminus of VP1 of HAV.
description:	Neutralization activity of antisera from animals immunized with epitope inserted into B-C loop of VP1 of type 1 poliovirus (PV-1) Sabin strain was assessed by HAV radioimmunofocus reduction assays.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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