Autoimmunity in Chagas disease cardiopathy: biological relevance of a cardiac myosin-specific epitope crossreactive to an immunodominant Trypanosoma cruzi antigen.

Title:

Autoimmunity in Chagas disease cardiopathy: biological relevance of a cardiac myosin-specific epitope crossreactive to an immunodominant Trypanosoma cruzi antigen.

Dataset

identifier:	1374684
description:	epitope description:NAAAAALDKKQRNFD antigen name:Myosin-7 host organism:Homo sapiens
aggregation:	instance of dataset
availability:	available
primaryPublications:	7536937

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1003893
landingPage:	http://www.iedb.org/assay/1374684

Publication

type:	Literature
publicationVenue:	Proc Natl Acad Sci U S A
dates:	1995

Dimension

study type:	b cell assays
subject species:	Homo sapiens

Person

fullName:	E Cunha-Neto M Duranti A Gruber B Zingales I De Messias N Stolf G Bellotti M E Patarroyo F Pilleggi J Kalil

Data Type

method:	antigen inhibition

Study

name:	Autoimmunity in Chagas disease cardiopathy: biological relevance of a cardiac myosin-specific epitope crossreactive to an immunodominant Trypanosoma cruzi antigen.
description:	This cardiac epitope inhibited the binding of sera from patients with chronic Chagas disease cardiomyopathy to the homologous T cruzi B13 protein.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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