Immunological Data Discovery Index
Immunological Data Discovery Index
| authorizations: |
registration not required
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| accessURL: |
http://www.iedb.org/reference/1003754 |
| landingPage: |
http://www.iedb.org/assay/1372650 |
| type: |
Literature
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| publicationVenue: |
Immunol Lett
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| dates: |
1998
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| study type: | b cell assays |
| subject species: | Leishmania infantum |
| fullName: |
L Quijada
J M Requena
M Soto
C Alonso
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| method: |
ELISA
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| name: |
Analysis of the antigenic properties of the L. infantum Hsp70: design of synthetic peptides for specific serodiagnosis of human leishmaniasis.
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| description: |
The sequence is from the reference: Quijada et al. (1996) Immunol. Letts. 52: 73-79.
Sera from 5 of 8 patients with mucocutaneous leishmaniasis and sera from 8 of 14 combined leishmaniasis (mucocutaneous and visceral) patients reacted with the epitope, whereas sera from 0 of 10 patients with Chagas' disease reacted with the epitope. However, sera from patients with leishmaniasis or Chagas' disease reacted with L. infantum Hsp70, which shares >85% sequence identity with T. cruzi Hsp70. The authors conclude that the epitope is a specific tool for differential serodiagnosis of visceral leishmaniasis and Chagas' disease.
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| name: |
iedb
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| homePage: |
http://www.iedb.org |
