A monoclonal antibody directed to terminal residue of beta-galactofuranose of a glycolipid antigen isolated from Paracoccidioides brasiliensis: cross-reactivity with Leishmania major and Trypanosoma cruzi.

Title:

Dataset

identifier:	1372751
description:	epitope description:beta-D-galactofuranosyl group antigen name:glycolipid host organism:Mus musculus BALB/c antibody name:MEST-1
aggregation:	instance of dataset
availability:	available
primaryPublications:	9184826

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1003760
landingPage:	http://www.iedb.org/assay/1372751

Publication

type:	Literature
publicationVenue:	Glycobiology
dates:	1997

Dimension

study type:	b cell assays
subject species:	Paracoccidioides brasiliensis

Person

fullName:	E Suzuki M S Toledo H K Takahashi A H Straus

Data Type

method:	western blot

Study

name:	A monoclonal antibody directed to terminal residue of beta-galactofuranose of a glycolipid antigen isolated from Paracoccidioides brasiliensis: cross-reactivity with Leishmania major and Trypanosoma cruzi.
description:	The epitope is the terminal residue of P. brasiliensis phosphoglyceroglycolipid Band 1 antigen. It is also found in other glycolipids as those from Leishmania and Trypanosoma. The epitope specific mAb MEST-1 binding to Band 1 antigen from yeast and mycelium forms. Similar results were obtained from RIA and immunofluorescence (IFA) staining. The binding was abolished after mild oxidation suggesting that binding is carbohydrate dependent.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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