Chimeric synthetic peptides as antigens for detection of antibodies to Trypanosoma cruzi. | ImmuneData Discovery Index

Immunological Data Discovery Index

Immunological Data Discovery Index

Title:

Chimeric synthetic peptides as antigens for detection of antibodies to Trypanosoma cruzi.

Dataset

identifier:	1372874
description:	epitope description:AEPKPAEPKS antigen name:Trans-sialidase, putative (UniProt:K4EAY0) host organism:Homo sapiens
aggregation:	instance of dataset
availability:	available
primaryPublications:	16289376

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1003857
landingPage:	http://www.iedb.org/assay/1372874

Publication

type:	Literature
publicationVenue:	Biochem Biophys Res Commun
dates:	2006

Dimension

study type:	b cell assays
subject species:	Trypanosoma cruzi

Person

fullName:	Milenen Herná ndez Marin Idialis Herná ndez Spengler Grisell Ramos Martí nez Lilliam Pozo Peñ a

Data Type

method:	ELISA

Study

name:	Chimeric synthetic peptides as antigens for detection of antibodies to Trypanosoma cruzi.
description:	The epitope sequence is repeated within the protein antigen. Sera from patients with HIV (0/20), HCV (0/20), HTLV-1 (0/20), toxoplasmosis (0/20), and leprosy (0/6) did not react with the epitope. Recognition was not increased to various constructs of the epitope coupled with another immunodominant B cell epitope from T. cruzi, PSPFGQAAAGDK.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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