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Title: Epitope mapping of trans-sialidase from Trypanosoma cruzi reveals the presence of several cross-reactive determinants.
identifier: 1374386
description:
epitope description:GPPVDPTSG
host organism:Oryctolagus cuniculus
antibody name:affinity-purified rabbit trans-sialidase (TcTS)
aggregation:
instance of dataset
availability:
available
primaryPublications: 11179365
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1003928
landingPage: http://www.iedb.org/assay/1374386
type:
Literature
publicationVenue:
Infect Immun
dates:
2001
study type: b cell assays
subject species:
fullName:
T A Pitcovsky
J Mucci
P Alvarez
M S Leguizamó
n
O Burrone
P M Alzari
O Campetella
method:
western blot
name:
Epitope mapping of trans-sialidase from Trypanosoma cruzi reveals the presence of several cross-reactive determinants.
description:
The epitope has homology to Trypanosoma cruzi trans-sialidase residues 411-418 and 529-539.
The epitope was selected from a phage display library of nonapeptides using T. cruzi (CAI and RA strains)-infected rabbit sera that was affinity purified on immobilized T. cruzi trans-sialidase (TcTS). Sera from 11 rabbits infected with several T. cruzi stocks reacted with phage bearing the mimotope.

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