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identifier: 1373158
description:
epitope description:H1530, Q1531, C1532, Q1539, N1540, S1541, C1543, H1546, L1547, E1549, R1550, E1551, C1553, L1557, N1558, E1562, K1565, C1566, C1601, K1605, S1608, F1612, D1613
antigen name:Merozoite surface protein 1
host organism:Mus musculus BALB/c
antibody name:12.8
aggregation:
instance of dataset
availability:
available
primaryPublications: 15500913
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1003629
landingPage: http://www.iedb.org/assay/1373158
type:
Literature
publicationVenue:
Mol Biochem Parasitol
dates:
2004
study type: b cell assays
subject species: Plasmodium falciparum isolate WELLCOME
fullName:
William D Morgan
Matthew J Lock
Thomas A Frenkiel
Munira Grainger
Anthony A Holder
method:
nuclear magnetic resonance (NMR)
name:
Malaria parasite-inhibitory antibody epitopes on Plasmodium falciparum merozoite surface protein-1(19) mapped by TROSY NMR.
description:
Transverse relaxation optimized spectroscopy (TROSY) NMR was carried out to identify residues for mAb binding. Binding sites of this parasite-inhibitory mAb were distinct from non-inhibitory mAb.

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