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identifier: 1373435
description:
epitope description:PFGQAAAGDKPS
host organism:Homo sapiens
aggregation:
instance of dataset
availability:
available
primaryPublications: 11390013
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1003926
landingPage: http://www.iedb.org/assay/1373435
type:
Literature
publicationVenue:
Peptides
dates:
2001
study type: b cell assays
subject species:
fullName:
L K Iwai
M A Duranti
L C Abel
M A Juliano
J Kalil
L Juliano
E Cunha-Neto
method:
antigen inhibition
name:
Retro-inverso peptide analogues of Trypanosoma cruzi B13 protein epitopes fail to be recognized by human sera and peripheral blood mononuclear cells.
description:
The peptide was synthesized by using D-aa instead of L-aa, maintaining the original order of the natural peptide from T. cruzi B13 Ag. Aa in the lower case are in the D-aa configuration.
This peptide has very low ability to compete the binding of Chagas' patients serum to immobilized recombinant B13 protein. The highest percentage of inhibition was found with the natural peptide.

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