The beta1 adrenergic effects of antibodies against the C-terminal end of the ribosomal P2beta protein of Trypanosoma cruzi associate with a specific pattern of epitope recognition.

Title:

The beta1 adrenergic effects of antibodies against the C-terminal end of the ribosomal P2beta protein of Trypanosoma cruzi associate with a specific pattern of epitope recognition.

Dataset

identifier:	1374410
description:	epitope description:EESDDDMGFGLFD antigen name:60S acidic ribosomal protein P2 host organism:Mus musculus
aggregation:	instance of dataset
availability:	available
primaryPublications:	16178868

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1003858
landingPage:	http://www.iedb.org/assay/1374410

Publication

type:	Literature
publicationVenue:	Clin Exp Immunol
dates:	2005

Dimension

study type:	b cell assays
subject species:	Homo sapiens

Person

fullName:	P Lopez Bergami K A Gó mez G V Levy V Grippo A Baldi M J Levin

Data Type

method:	ELISA

Study

name:	The beta1 adrenergic effects of antibodies against the C-terminal end of the ribosomal P2beta protein of Trypanosoma cruzi associate with a specific pattern of epitope recognition.
description:	Sera from BALB/c and Swiss mice immunized with TcP2beta bound the epitope. Mice were described as Chagas'-like (anti-TCP2B+,-R13+, and -H13+), non-responders, or having an autoimmune phenotype (anti-TCP2B+,-R13+, -C10+, and -H13+). The autoimmune phenotype responded best to the epitope and the non-responders did not recognize the epitope. Reactivity towards the epitope was first detected at day 52 post-immunization.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

Feedback?

If you are having problems using our tools, or if you would just like to send us some feedback, please post your questions on Feedback.

Related Publications

Feedback?