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Title: Epitope mapping of trans-sialidase from Trypanosoma cruzi reveals the presence of several cross-reactive determinants.
identifier: 1374615
description:
epitope description:NPIDATARS
host organism:Mus musculus BALB/c
antibody name:anti-peptide 1445 (B23)
aggregation:
instance of dataset
availability:
available
primaryPublications: 11179365
authorizations:
registration not required
accessURL: http://www.iedb.org/reference/1003928
landingPage: http://www.iedb.org/assay/1374615
type:
Literature
publicationVenue:
Infect Immun
dates:
2001
study type: b cell assays
subject species:
fullName:
T A Pitcovsky
J Mucci
P Alvarez
M S Leguizamó
n
O Burrone
P M Alzari
O Campetella
method:
western blot
name:
Epitope mapping of trans-sialidase from Trypanosoma cruzi reveals the presence of several cross-reactive determinants.
description:
. The epitope is homologous to T. cruzi trans-sialidase residues 397-405, which forms a loop connecting the two structural domains of the enzyme.
Sera from mice immunized with epitope-KLH conjugate reacted weakly with peptide 1439 (YSVDDGETWC) based on residues 69-77 of T. cruzi trans-sialidase with an added C-terminal Cys.

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