Dominant T- and B-cell epitopes in an autoantigen linked to Chagas' disease. | ImmuneData Discovery Index

Immunological Data Discovery Index

Immunological Data Discovery Index

Title:

Dominant T- and B-cell epitopes in an autoantigen linked to Chagas' disease.

Dataset

identifier:	1376396
description:	epitope description:MRQLDTNVER antigen name:Transcription factor-like 5 protein host organism:Homo sapiens antibody name:chagasic anti-R3 affinity-purified antibody
aggregation:	instance of dataset
availability:	available
primaryPublications:	11306602

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1003927
landingPage:	http://www.iedb.org/assay/1376396

Publication

type:	Literature
publicationVenue:	J Clin Invest
dates:	2001

Dimension

study type:	b cell assays
subject species:	Homo sapiens

Person

fullName:	N Gironè s C I Rodrí guez E Carrasco-Marí n R F Herná ez J L de Rego M Fresno

Data Type

method:	antigen inhibition

Study

name:	Dominant T- and B-cell epitopes in an autoantigen linked to Chagas' disease.
description:	The mouse peptide R3M (IRQLDTSVERRALGEIQNV) inhibited the binding of human chagasic sera or chagasic sera, affinity-purified with the epitope, from binding to the human R3H peptide (MRQLDTNVERRALGEIQNV), which contains the epitope.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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