Antibody-resistant mutations in cross-reactive and type-specific epitopes of herpes simplex virus 1 glycoprotein B map in separate domains.

Title:

Antibody-resistant mutations in cross-reactive and type-specific epitopes of herpes simplex virus 1 glycoprotein B map in separate domains.

identifier:	1376719
description:	epitope description:APTGDTKPKKNKKPKNP antigen name:Envelope glycoprotein B host organism:Mus musculus BALB/c antibody name:H1392, H1396, H1397
aggregation:	instance of dataset
availability:	available
primaryPublications:	2459843

study type:	b cell assays
subject species:	Herpes simplex virus (type 1 / strain F)

fullName:	K G Kousoulas B Huo L Pereira

method:	biological activity

name:	Antibody-resistant mutations in cross-reactive and type-specific epitopes of herpes simplex virus 1 glycoprotein B map in separate domains.
description:	The authors conclued that the 3 mAbs recognize epitopes located at this continuous stretch based on SDS-PAGE, immunoprecipitation and neutralization assays for the WT virus strain F and its escape mutants harboring single mutations, and by comparison with the sequence found in HSV-1 KOS and HSV-2 G, not recognized by these mAbs.

name:	iedb
homePage:	http://www.iedb.org

If you are having problems using our tools, or if you would just like to send us some feedback, please post your questions on Feedback.