Virus neutralizing activity induced by synthetic peptides of glycoprotein D of herpes simplex virus type 1, selected by their reactivity with hyperimmune sera from mice.

Title:

Virus neutralizing activity induced by synthetic peptides of glycoprotein D of herpes simplex virus type 1, selected by their reactivity with hyperimmune sera from mice.

Dataset

identifier:	1378306
description:	epitope description:WFRMGGNAAIPITVMEYTE + NLeu(M4,M15) host organism:Mus musculus BALB/c antibody name:anti-HSV-1
aggregation:	instance of dataset
availability:	available
primaryPublications:	2167930

Access

authorizations:	registration not required
accessURL:	http://www.iedb.org/reference/1004006
landingPage:	http://www.iedb.org/assay/1378306

Publication

type:	Literature
publicationVenue:	J Gen Virol
dates:	1990

Dimension

study type:	b cell assays
subject species:

Person

fullName:	H J Geerligs C H Kocken J W Drijfhout W J Weijer W Bloemhoff J B Wilterdink G W Welling S Welling-Wester

Data Type

method:	ELISA

Study

name:	Virus neutralizing activity induced by synthetic peptides of glycoprotein D of herpes simplex virus type 1, selected by their reactivity with hyperimmune sera from mice.
description:	The sequence is based on human herpesvirus 1 mature glycoprotein D (gD-1) residues 99-117 with a Cys to Ala substitution at residue 106 and Met to norleucine substitution at residues 102 and 113 . Sera from 2 of 10 mice that had been immunized with heat-inactivated HSV-1 and survived challenge with 1.1 x 10^8 p.f.u. HSV-1 reacted with the epitope.

Data Repository

name:	iedb
homePage:	http://www.iedb.org

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